How Can Information Extraction Ease Formalizing Treatment Processes in Clinical Practice Guidelines? A Method and its Evaluation

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Abstract
Objective. Formalizing clinical practice guidelines for a subsequent computer-supported processing is a challenging, but burdensome and time-consuming task. Existing methods and tools to support this task demand detailed medical knowledge, knowledge about the formal representations, and a manual modeling. Furthermore, formalized guideline documents mostly fall far short in terms of readability and understandability for the human domain modeler. Methods and Material. We propose a new multi-step approach using information extraction methods to support the human modeler by both automating parts of the modeling process and making the modeling process traceable and comprehensible. This paper addresses the first steps to obtain a representation containing processes which is independent of the final guideline representation language. Results. We have developed and evaluated several heuristics without the need to apply Natural Language Understanding and implemented them in a framework to apply them to several guidelines from the medical subject of otolaryngology. Findings in the evaluation indicate that using semi-automatic, step-wise information extraction methods are a valuable instrument to formalize CPGs. Conclusions. Our evaluation shows that a heuristic-based approach can achieve good results, especially for guidelines with amajor portion of semi-structured text. It can be applied to guidelines irrespective to the final guideline representation format. Key words: Information extraction and integration, clinical practice guidelines, computer-interpretable guidelines, guideline representation, treatment processes, time-oriented information, otolaryngology
Year of Publication
2007
Journal
Special issue of the Journal of Artificial Intelligence in Medicine (AIIM), Theme: Conference on Artificial Intelligence in Medicine (AIME 05)
Volume
39
Number
Number of Pages
151–163
Type of Article
Refereed Journal Articles
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http://www.cvast.tuwien.ac.at/sites/default/files/publications/PDF/2007/aiim_2007/kaiser_2006_aiim_lassie.pdf